Effects on hemodynamic variables and echocardiographic parameters after a stellate ganglion block in 15 healthy volunteers

摘要

Background: The sympathetic nervous system has an important role in generating pain. Various\udpathomechanisms are involved that respond well to the application of local anesthetics (LA), for example to\udthe stellate ganglion block (SGB).\udObjectives:We wanted to know more about the effects of SGB on cardiovascular parameters.\udMethods:Weincluded 15 healthy volunteers; another 15 healthy volunteers as a control group (shaminjection of\udLA). In order to produce a more precise SGB, we employed only a small volume of LA (3 mL), a LA with a lower\udpermeability (procaine 1%), and amodified injection technique. Systolic and diastolic blood pressure (SBP, DBP),\udheart rate (HR), and echocardiographic parameters were recorded before and after SGB. We also investigated\udwhether there are side differences (left and right SBG).\udResults: At baseline all parameterswere within the normal range. After performing right and left SGB DBP significantly\udincreased (on the right side from68.73±8.61 to 73.53±11.10, p=0.015; on the left side from70.66±\ud13.01 to 77.93 ± 10.40, p = 0.003). In the control group no increase in DBP was observed. No side-specific differences\udwere found, except a significant reduction in the maximum velocity of myocardial contraction during\udthe systole with left-sided SGB.\udConclusions: Even with our methods we could not prevent the simultaneous occurrence of a partial\udparasympatholytic effect. For this reason, the SGB has only minor hemodynamic effects, which is desirable as it\udenhances the safety of the SGB.